Download A Symposium on Mechanisms of Toxicity by W. N. Aldridge (eds.) PDF

By W. N. Aldridge (eds.)

ISBN-10: 1349010871

ISBN-13: 9781349010875

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18, 2559 TIPTON, K. F. & SPIRES, I. P. C. (1968). Biochem. , 17,2137 YouDIM, M. B. , CoLLINS, G. G. S. & SANDLER, M. (1969). , 223, 626 YoUDIM, M. B. H. & SouRKES, T. L. (1966). Can. J. , 44, 1397 ZELLER, E. A. (1951). In The Enzymes, vol. 2, Part 1, p. 536, ed. Sumner, J. B. , New York: Academic Press ZELLER, E. , BLANKSMA, L. , BURKARD, w. , PACHA, w. L. & LAZANAS, J. C. (1959). Ann. Y. Acad. , 80, 583. SOME NEW EFFECTS OF ANTICHOLINESTERASES IN THE WHOLE ANIMAL, WITH SPECIAL EMPHASIS ON THE HYPOTHERMIA INDUCING ACTION IN THE RAT E.

Acta physiol. pharmac. , 15, 55 PREUSSER, H. J. (1967). Z. , 80, 436 Anticholinesterases in Hypothermia RAND, R. , BURTON, A. C. & lNG, T. (1965). Can. J. Physiol. , 43, G. & HIRSCHOWITZ, B. I. (1965). Proc. Soc. exp. Bioi. , SPAAN, G. & KLUSSMANN, F. W. (1969). Pfliigers Arch. ges. , 312, 1 WERNER, G. & KUPERMAN, A. S. (1963). In Handbuch der Experimentellen Pharmakologie, vol. 15, ed. Koelle, G. , pp. 57Q-678. Berlin: Springer Verlag WoLTHUIS, 0. L. & MEETER, E. (1968). Eur. J. , 2, 387 ZETLER, G.

B. Rowe, J. D. Gass, & S. L. N. '\.. -· w....... 1:. ,, 20 ) .... , 0 Time(minl FIG. 8. Effect of glutamate, ammonia and hydroxylamine on the inhibition of glutamine synthetase by methionine sulphoximine. (a) Glutamate and NH 3 : curve 1 (0-0): a reaction mixture (0·1 ml) containing enzyme (3·8 (LM), MgC12 (0·02 M), 2-mercaptoethanol (0·01 M), and imidazole-HCl buffer {0·05 M, pH 7·2) was placed at 37°C for 5 min. Then a solution (0·002 ml) containing L-methionine sulphoximine (0·025 M) and NaATP (0·5 M) was added, and the mixture was incubated at 37°C.

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